Defining and validating chronic diseases
We included all practices in England that had been using the EMIS computer system for at least one year and randomly allocated three quarters of practices to the derivation dataset and the remainder to a validation dataset.
Participants 1309 QResearch general practices in England: 981 practices were used to develop the scores and a separate set of 328 practices were used to validate the scores.We also considered erectile dysfunction diagnosis or treatment in men.Measures of calibration and discrimination were determined in the validation cohort for men and women separately and for individual subgroups by age group, ethnicity, and baseline disease status.7.89 million patients aged 25-84 years were in the derivation cohort and 2.67 million patients in the validation cohort.Patients were free of cardiovascular disease and not prescribed statins at baseline.
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